In Avogadro put forward a hypothesis that was neglected by his contemporaries for years. Avogadro, however, saw it as the key to a better understanding of molecular constituency. In Avogadro hypothesized that equal volumes of gases at the same temperature and pressure contain equal numbers of molecules. From this hypothesis it followed that relative molecular weights of any two gases are the same as the ratio of the densities of the two gases under the same conditions of temperature and pressure. Avogadro also astutely reasoned that simple gases were not formed of solitary atoms but were instead compound molecules of two or more atoms. Avogadro did not actually use the word atom ; at the time the words atom and molecule were used almost interchangeably.
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Although a schoolteacher, a meteorologist, and an expert on color blindness, John Dalton is best known for his pioneering theory of atomism. He also developed methods to calculate atomic weights and structures and formulated the law of partial pressures. Dalton — was born into a modest Quaker family in Cumberland, England, and for most of his life—beginning in his village school at the age of 12—earned his living as a teacher and public lecturer. After teaching for 10 years at a Quaker boarding school in Kendal, he moved on to a teaching position in the burgeoning city of Manchester. There he joined the Manchester Literary and Philosophical Society, which provided him with a stimulating intellectual environment and laboratory facilities. The first paper he delivered before the society was on color blindness, which afflicted him and is sometimes still called Daltonism. Dalton arrived at his view of atomism by way of meteorology, in which he was seriously interested for a long period: he kept daily weather records from until his death, his first book was Meteorological Observations , and he read a series of papers on meteorological topics before the Literary and Philosophical Society between and
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