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Marburg Files: The Documents That Revealed King Edward VIII's Nazi Ties
Due to optimized operational efficiencies which were initiated last year, BioNTech has been able to increase the expected annual manufacturing capacity by million doses. A single mRNA batch of the current scale is sufficient to produce around eight million vaccine doses. Based on the approval by the EMA, first drug product batches of the vaccine can now be delivered to partner sites for sterile fill and finish, before distribution to the European Union and countries worldwide. The first batches of vaccines manufactured at the Marburg site are expected to be delivered in the second half of April. In total, 50, steps are required from manufacturing the mRNA to the bulk drug substance which then can be handed over for fill and finish.
Marburg virus disease is a deadly, but rare, hemorrhagic fever similar to Ebola. While the disease typically starts out like many other tropical illnesses with fever and body aches, it can quickly lead to severe bleeding, shock, and death. As many as nine in 10 people with the virus die as a result of the infection. Outbreaks of Marburg virus are extremely uncommon.
The mile canal, a commercial shipping hub connecting the Mediterranean and Red Seas, was crucial to English economic interests, particularly since it facilitated the all-important flow of oil. Originally opened in , it had been jointly controlled by Britain and France—even after Egypt gained independence in The British were loathe to lose it, and the international influence it signaled. While it initially appeared that French and British forces joined the Israelis two days after their incursion, it was later revealed that the three powers had met and planned the attack altogether.